Enclomiphene Therapy

Adjunct or Alternative to Testosterone Replacement Therapy (TRT)


Enclomiphene Therapy

Enclomiphene is a selective estrogen receptor modulator (SERM) that has been investigated for its potential use in treating low testosterone levels in men. It works by stimulating the production of endogenous testosterone by the testes. Enclomiphene is an isomer of clomiphene, a medication that has been used in the treatment of female infertility.

Here's how enclomiphene therapy...

Enclomiphene is a selective estrogen receptor modulator (SERM) that has been investigated for its potential use in treating low testosterone levels in men. It works by stimulating the production of endogenous testosterone by the testes. Enclomiphene is an isomer of clomiphene, a medication that has been used in the treatment of female infertility.

Here's how enclomiphene therapy works for low testosterone:

  1. Estrogen Receptor Blockade: Enclomiphene primarily acts by blocking estrogen receptors in the hypothalamus and pituitary gland. This leads to an increase in the release of gonadotropins, such as luteinizing hormone (LH) and follicle-stimulating hormone (FSH), from the pituitary gland.

  2. Stimulation of Testosterone Production: The increased levels of LH and FSH stimulate the Leydig cells in the testes to produce more testosterone. This is different from direct testosterone replacement therapy (TRT), where exogenous testosterone is administered.

Enclomiphene is being studied as an alternative to traditional testosterone replacement therapy, aiming to avoid some of the potential side effects associated with TRT, such as testicular atrophy and suppression of the body's natural testosterone production.

It's important to note that enclomiphene is not yet widely approved for the treatment of low testosterone, and its use is still being investigated in clinical trials. Additionally, the long-term safety and effectiveness of enclomiphene for treating low testosterone have not been fully established.

If you are considering enclomiphene therapy or any other treatment for low testosterone, it's crucial to consult Raman Dhillon, MD "The Testosteronologist" and her team of "Testosteronologists" at Peak Life Health. They will assess your specific situation, conduct necessary tests, and provide the most appropriate course of action based on your individual needs and health status. Additionally, they will discuss potential risks and  benefits with you.

Enclomiphene therapy aims to boost your own (endogenous) production of testosterone. It is a better alternative to Clomiphene. It is actually a the trans- isomer of clomiphene citrate and has higher potency in stimulating the hypothalamic-pituitary-gonadal axis. This property enables enclomiphene citrate to increase your testosterone levels more than clomephene while minimizing estrogen-related side effects.
Enclomiphene is important if you want to preserve fertility while on testosterone replacement therapy (TRT). Enclomiphene increases testosterone production, improves sperm production, libido, erection strength, testicular volume, and ejaculate volume.


Dealing with low testosterone is tough. Lack of energy, muscle loss, weight gain, low sex drive, and brain fog can make you feel irritated and confused. Unfortunately, many people don’t pay attention to these symptoms until the problem worsens. Consulting a doctor at the right time can help you manage these symptoms and get back to your healthy self.

Peak Life Health is a reputable enclomiphene therapy provider in Garland, Sunnyvale, Mesquite, Forney, and the DFW area, TX. This treatment can help you boost the natural testosterone production in your body and help you feel like your best self again.

What is Enclomiphene?

Enclomiphene is an isomer of clomiphene, which is a type of medication called a selective estrogen receptor modulator (SERM). It belongs to a class of compounds known as non-steroidal anti-estrogens. 

Only active enclomiphene isomer of clomiphene can selectively attach to and block estrogen receptors in the hypothalamus and pituitary glands in the brain. These glands regulate the production of hormones, including testosterone and estrogens. 

When a man has a high estrogen level, it starts a negative feedback loop that suppresses the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the pituitary gland. As enclomiphene blocks the estrogen receptors, it stops this negative feedback loop and promotes the release of FSH and LH. Then, FSH and LH stimulate the testes to increase testosterone production. 

What is Enclomiphene Therapy?

Enclomiphene therapy is used to treat the main cause of low testosterone levels. It stimulates your body to produce natural testosterone. This therapy reactivates your hypothalamic-pituitary-gonadal axis (HPGA), the system that regulates testosterone. It tricks your body into believing that the testosterone level in your body is low and promotes FSH and LH release. These hormones stimulate your testicles to make more testosterone and restore your natural hormone balance.

Who Needs Enclomiphene Therapy?

Enclomiphene therapy can help men experiencing symptoms, including:

  • Decreased muscle and strength
  • Increased belly fat and weight gain
  • Low sex drive and libido
  • Testicular dysfunction
  • Fatigue and low energy
  • Mood issues like irritability and depression
  • Concentration and cognitive problems

The causes of these symptoms can be testicular disorders, pituitary issues, obesity, aging, and conditions affecting testicular size/function. Peak Life Health offers customized enclomiphene therapy in Texas (DFW area). If you are experiencing these signs or symptoms, book an appointment with us today.

Benefits of Enclomiphene Testosterone Booster Therapy

  • Increases testosterone levels
  • Promotes natural testosterone production
  • Boosts libido
  • Improves erectile function
  • Builds greater muscle mass and increases strength
  • Improves mood
  • Improves energy levels
  • Maintains fertility in men
  • Promotes fat loss
  • Restores vitality
  • Balances hormones
  • Increases confidence and motivation
  • Improves bone density
  • Supports healthier cholesterol levels

Enclomiphene and Testosterone Replacement Therapy

Enclomiphene and testosterone therapy are not the same, although they both treat low testosterone levels. 

Testosterone Replacement Therapy (TRT) is mostly used when:

  • Testosterone levels are extremely low due to conditions like hypogonadism or androgen deficiency.
  • Restoring testosterone levels is essential for relieving symptoms like low sex drive, fatigue, muscle loss, etc.
  • Fertility is not an immediate concern, as TRT can temporarily impair sperm production.

Enclomiphene Therapy may be recommended when:

  • Testosterone levels are moderately low, but the body is still producing some testosterone naturally.
  • Increasing testosterone through the body's production mechanisms is preferred.
  • Maintaining or boosting fertility is a priority, as enclomiphene does not impair sperm production.
  • Avoiding some of the potential side effects associated with external testosterone.

Our enclomiphene therapy clinic in Garland, Sunnyvale, Mesquite, Forney, and the DFW area, TX, can help you find which approach may be most suitable for you.

What to Expect with Our Enclomiphene Therapy

We do a thorough diagnosis to see if Enclomiphene Therapy is right for you. Dr. Raman Dhillon, MD, our certified doctor for enclomiphene therapy, will understand your condition and provide a solution. 

Our diagnostic process includes:

  • Reviewing your medical history, symptoms, and test results.
  • Measuring testosterone and other hormone levels.
  • Checking overall health and identifying underlying conditions with physical exam.
  • Specialized testing like imaging or genetics to find the root cause (if required).

If enclomiphene therapy is right for you, here's what to expect:

  • Open discussion about dosage, potential side effects, and lifestyle recommendations.
  • Enclomiphene prescription with instructions for proper use.
  • Follow-up appointments to track your progress and adjust the treatment.
  • Guidance on healthy habits like exercise, stress management, and diet for hormone balance.
  • Ongoing support from our team to address concerns and ensure optimal results.

Solutions for your low testosterone and other hormonal issues are available. You do not have to accept your symptoms as an inevitable result of aging.

Book an Appointment Today | Enclomiphene Therapy in Texas, DFW Area

Let Peak Life Health provide you with the best treatment for your hormonal issues. Our expert doctors will make sure that you are comfortable sharing your problems.

See the doctor for enclomiphene therapy in Garland, Sunnyvale, Mesquite, Forney, and the DFW area, TX. To learn more about Peak Life Health, book an appointment or call +14696308733


  • No downtime
  • No discomfort
  • Results can be felt within 1 - 2 days.
  • Every 3 months


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